子供の病気119番 〜 小児科疾患マニュアル

子供の病気119番 〜 小児科疾患マニュアル
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研究業績(和文)

I. EBウイルス関連

1. 菊田英明: EBウイルスのヒト単核球接種によるインターフェロンの産生と産生インターフェロンによるEBウイルストランスフォーメーションの抑制、北海道医学雑誌 61,46-57, 1986


2. 菊田英明、小島公一、田口裕一、富沢一浩、川村信明、石坂明人、崎山幸雄、松本脩三、木下俊文、水野文雄、大里外誉郎、平井莞二:わが国において分離されたEBウイルスの型. 医学のあゆみ 144, 991-992, 1988


3. 崎山幸雄、 菊田英明、川村信明、 松本脩三:感染免疫に関連した2、3の話題、小児科学年鑑 小児科の進歩 8, 79-83, 1988


4. 菊田英明、松本脩三:EBウイルスゲノム陽性Tリンパ球の存在とEBウイルス持続感染、 小児科学年鑑 小児科の進歩 9, 204-206, 1989


5. 菊田英明、陸華:Epstein-Barrウイルス抗体価、検査と技術 17, 1326-1327, 1989


6. 菊田英明、松本脩三: Epstein-Barrウイルスゲノム陽性Tリンパ球、医学のあゆみ 151, 548, 1989


7. 菊田英明、大鹿栄樹、田口裕一、富沢一浩、小島公一、仲西正憲、川村信明、石坂明人、崎山幸雄、松本脩三、武田武夫、柳沢光彦、矢崎信、 加藤敏行:慢性活動性Epstein-Barrウイルス(EBV)感染症から分離されたEBV-DNAの解析、日本小児科学会雑誌 93, 253-257, 1989


8. 陸華、菊田英明、崎山幸雄、松本脩三: neurotropinのEpstein-Barrウイルスによるトランスフォーメーションにおよぼす抑制作用、臨床免疫 21, 1982-1985, 1989


9. 菊田英明: ウイルスの核酸検出法、小児科診療 54, 957-961, 1991


10. 菊田英明: EBウイルス感染症、検査と技術 20, 558-562, 1992


11. 菊田英明:慢性活動性EBウイルス感染症の病態と検査、Medical Technology 22, 837, 1994


12. 菊田英明:EBウイルス感染症,検査と技術 24, 223-226, 1996


13. 菊田英明:Epstein-Barr virus-associated hemophagocytic syndrome、小児内科 28, 1604-1607, 1996


14. 板倉治,菊田英明:EBウイルス関連疾患のEBウイルスLMP-1 C末端の遺伝子解析、日本臨床 55, 197-202, 1997


15. 菊田英明:伝染性単核症、臨床と微生物 26, 483-486, 1999


16. 菊田英明:ウイルス関連貪食症候群、KEY WORD 1997-'98 感染症、26-27, 1998


17. 菊田英明: 小児科におけるヒトヘルペスウイルス感染症、ウイルス感染症セミナー1: 17-22, 1999


18. 吉岡幹朗、菊田英明:慢性活動性EBウイルス感染症、炎症と免疫 8, 528-532, 2000


19. 菊田英明:伝染性単核症、慢性活動性EBウイルス感染症、212-213(矢田純一、柳沢正義、山口規容子、大関武彦編:今日の小児治療指針、第12版、医学書院、東京)2000


20. 菊田英明: EBウイルス関連・非腫瘍性Tリンパ球増殖性疾患−慢性活動性EBウイルス感染症・EBウイルス関連血球貪食症候群−、123-138(柳井秀雄、清水則夫編:EBウイルス、診断と治療社、東京)2003


21. 菊田英明:免疫不全とリンパ腫、日本小児皮膚科学会雑誌 23, 161-163, 2004


22. 菊田英明:EBV感染症の診断、日本臨床 64巻、増刊号3, 617-620, 2006


23. 菊田英明。慢性活動性EBウイルス感染症とT細胞増殖症。54-60(河敬世 編:新しい診断と治療のABC 46:潜伏感染ウイルスによる血液疾患、血液5、最新医学社、大阪)2007


24. 菊田英明: EBウイルス関連・非腫瘍性Tリンパ球増殖性疾患−慢性活動性EBウイルス感染症・EBウイルス関連血球貪食症候群−、改定第2版、100頁−108頁(柳井秀雄、清水則夫編:EBウイルス、診断と治療社、東京)2008


II. ヒト・メタニューモウイルス関連

1. 海老原敬、菊田英明:Human metapneumovirus気道感染症、小児科 44, 1252-1257, 2003


2. 菊田英明:ヒト・メタニューモウイルス。感染・炎症・免疫 34巻、1号, 82-87,  2004


3. 菊田英明:ヒト・メタニューモウイルス感染症、Medical Corner 115巻, 2号, 23-25, 2004


4. 菊田英明:「特集 新しい感染症」ヒト・メタニューモウイルス 東京小児科医会報、23巻2号、15-18, 2004

5. 海老原敬、菊田英明: ヒト・メタニューモウイルス. 日本胸部臨床 2004年増刊S69-S71


6. 菊田英明:ヒト・メタニューモウイルス感染症。小児科 46, 77-81, 2005


7. 海老原敬、菊田英明:ヒト・メタニューモウイルス感染症の臨床像、小児内科 37, 103-106, 2005


8. 菊田英明:小児ヒト・メタニューモウイルス感染症のウイルス学的、臨床学的検討、小児感染免疫、17巻、3号、220-224, 2005


9. 菊田英明:ヒト・メタニューモウイルス感染症。月刊 母子保健 2005年5月号 4-5


10. 高橋豊、佐藤宏紀、川原朋乃、藤原ふみえ、鹿野高明、海老原敬、石黒信久、菊田英明:Human metapneumovirusが発作誘発に関与したと考えられた

小児喘息患児の検討。メディカルレビュー社。喘息 18巻, 2号, 2005-4, 77-80.


11. 菊田英明:ヒト・メタニューモウイルス感染症、ウイルス感染症セミナー 7: 9-12, 2005


12. 菊田英明:ヒトメタニューモウイルス感染症、260-261(大関武彦、古川漸、横田俊一郎編:今日の小児治療指針、第14版、医学書院、東京) 2006


13. 菊田英明:ヒト・メタニューモウイルス感染症、小児科診療69、増刊号、小児の治療指針、191-194, 2006


14. 菊田英明:ヒト・メタニューモウイルス呼吸器感染症、Medical Technology 34巻、7号、686, 2006


15. 菊田英明:ヒト・メタニューモウイルス感染症-病態解明とその制御に向けて-、小児感染免疫 18巻、2号、167-171, 2006


16. 菊田英明:ヒト・メタニューモウイルス、ウイルス 第56巻、第2号、173-182, 2006


17. 菊田英明:ヒト・メタニューモウイルス感染症、臨床とウイルス 第34巻、第5号、409-416, 2006


18. 高橋豊、羽田美保、米川元晴、田端祐一、鹿野高明、海老原敬、遠藤理香、石黒信久、菊田英明。小児human metapneumovirusおよびrespiratory syncytial virus感染症の臨床像の比較。小児科。第47巻、第7号、1115-1120, 2006


19. 菊田英明。ヒトメタニューモウイルス。日常診療に役立つ小児感染症マニュアル 2007.日本小児感染症学会編。381-387


20. 菊田英明。新しい呼吸器ウイルス:ヒトメタニューモウイルスとヒトボカウイルス。こどもの感染症の診かた。小児下気道感染症。2007. 6, Vol. 6, p19-20.


21. 菊田英明。ヒトメタニューモウイルス、ヒトボカウイルス。臨床と微生物。34, 307-310,2007


22. 菊田英明。RSウイルス・ヒトメタニューモウイルス。小児感染症学(岡部信彦 編)

406―411、2007年


23. 菊田英明:人・メタニューモウイルス感染症。MyMedical

http://www.mymed.jp/di/g4c.html


24. 菊田英明。ヒトメタニューモウイルス感染症。小児科診療。70, 2313-2317, 2007


25. 菊田英明。新しい呼吸器ウイルス:ヒトメタニューモとボカウイルス感染症。化学療法の領域。24巻。62-67, 2008


26. 菊田英明。乳幼児の呼吸器感染症の原因となる新たなウイルスの発見。Pedi! Vol.22, P4-6


27. 菊田英明:新しい呼吸器感染症ウイルス −ヒト・メタニューモウイルスを中心にして− 札医通信。496巻、8-10, 2008


28. 石黒信久、遠藤里香、菊田英明:肺炎を起こすウイルス。診断と治療。97巻。456-461, 2009


29. 菊田英明:ヒトメタニューモウイルス感染症。日本胸部臨床。69巻、9号、834-842, 2010.


30.菊田英明:ヒトメタニューモウイルス感染症。小児科臨床ピクシス 25。小児感染症。 106-109. 2011


31. 菊田英明。ヒトメタニューモウイルス、ヒトボカウイルスなどの新しい感染症。小児感染症学(改定第2版)(岡部信彦 編)342-376、2011年


32. 菊田英明。ヒトメタニューモウイルス。臨床とウイルス. 第39巻、第4号、193-200, 2011.


33. 菊田英明。ヒトメタニューモウイルス。日常診療に役立つ小児感染症マニュアル 2012。日本小児感染症学会編。P424-431


34. 菊田英明。ヒトメタニューモウイルス感染症。小児内科  44巻増刊号 (2012年増刊号) 小児疾患の診断治療基準 改定4版。358-359.


35. 近年発見されたヒトメタニューモウイルスの基礎と臨床。小児内科。44巻、7月増大号。特集 クローズアップ感染症。1003-1006。2012


36. 新しい呼吸器ウイルス感染症−ヒトメタニューモウイルスを中心に−日本小児科医会会報 2012. 第44号。27-31


37. 菊田英明。MEDI QUIZ日経メディカル 2013; 2: 121-122


38. ヒト・メタニューモウイルス発見から12年が経過して。北海道小児科医会会報2013。第29号。9-13.

http://www.touei.or.jp/pdf/hMPV_12year.pdf


39. 菊田英明。ヒト・メタニューモウイルス感染症。モダンメディア  51巻9号2005〔感染症〕  217-222

http://www.eiken.co.jp/modern_media/backnumber/pdf/MM200509_02.pdf


40. 菊田英明。迅速ヒトメタニューモウイルス診断キット−保険適用されたイムノクロマト法によるhMPV抗原定性− Modern Media 2014、60巻、1-5ページ

http://www.eiken.co.jp/modern_media/backnumber/pdf/MM1405_01.pdf


41. 菊田英明。呼吸器感染症の中のヒトメタニューモウイルス感染症-迅速hMPV抗原検査の保険適応- 愛知県小児科医会会報。2014;No. 100: 37-42


42. 菊田英明。ヒトメニューモウイルス。臨床医のための呼吸器・消化器ウイルス感染症。2014。診断と治療社。9-13ページ


43. 菊田英明。ヒトメニューモウイルス感染症。小児内科2014。小児疾患のための病態生理1。1098-1100ページ。


44. 菊田英明。ヒトメニューモウイルス(Human metapneumovirus: hMPV)を知っていますか?保育と保険ニュース 2014年11月15日。4ページ


45. ラジオNIKKEI: 2014年11月26日放送 「ヒトメタニューモウイルス感染症の臨床的特徴と診断・治療」

http://medical.radionikkei.jp/kansenshotoday_pdf/kansenshotoday-141126.pdf


46. 菊田英明。ヒトメタニューモウイルス感染症。小児科診療 2015。78巻。 1331-1335


47. 菊田英明。迅速ヒトメタニューモウイルス診断キット −呼吸器感染症でどのように使用するか?−2015年68巻。2705-2710


48. 菊田英明。ヒトメタニューモウイルス感染症。小児科診療ガイドライン−最新の診療指針−第3版。2016年。92-95


III. 川崎病関連

1. 菊田英明、古賀康嗣、今野武津子、石川信義、畑中宗博: MCLSにおける末梢血リンパ球のADCC活性 ―マイクロプレート法での検討−、小児科臨床 35, 1450-1452, 1982


2. 菊田英明、水野文雄、大里外誉郎、今野武津子、石川信義、南部春生、穴倉廸弥、岡洋瑚、松本脩三、野呂新一、桜田教夫:川崎病の発症とEBウイルス初感染、日本臨床 41, 109-114, 1983 


3. 菊田英明、松本脩三、大里外誉郎:川崎病の原因 −EBウイルス−、医学のあゆみ 130, 522, 1984


4. 菊田英明: 川崎病とEBウイルス初感染の異常について、近畿川崎病研究会、 川崎病 6, 1-2, 1984 


5. 水野文雄、菊田英明、大里外誉郎: EBウイルス抗体像からみた川崎病、臨床とウイルス12, 236-238, 1984


6. 菊田英明、松本脩三:川崎病の再発とEBウイルス関連抗体の動き、 Progress in Medicine 5, 116-120, 1985 


7. 菊田英明、崎山幸雄、松本脩三、水野文雄、大里外誉郎、今野武津子、石川信義、柳瀬義男、川崎富作: 川崎病再発例とEBウイルス関連抗体の動き、医学のあゆみ 132,586-587, 1985


8. 菊田英明、崎山幸雄、松本脩三、水野文雄、大里外誉郎、今野武津子、石川信義、卯月勝弥、南部春生、穴倉廸弥: 川崎病にみられるEBウイルス関連抗体像の特殊性とその解釈、日本小児科学会雑誌 89, 1905-1922, 1985


9. 菊田英明、松本脩三、水野文雄、大里外誉郎、今野武津子、石川信義:EBウイルスが検出された川崎病の4症例、医学のあゆみ 134, 1092-1094, 1985


10. 崎山幸雄、岡野素彦、菊田英明、長谷直樹、松本脩三:川崎病長期観察例におけるEBウイルス関連抗体価、医学のあゆみ 144, 703-704, 1988


11. 松本脩三、野々山恵章、菊田英明: 川崎病の免疫病態、Progress in Medicine 9, 105-109, 1989


12. 菊田英明: 川崎病様の冠動脈瘤を伴った慢性活動性EBV感染症、Labeam (SRL)、6、1-3、1994


13. 菊田英明:川崎病の病因の一つとしてEpstein-Barrウイルス(EBV)が報告されていましたが、本当でしょうか、小児内科 35, 1480-1482, 2003


14. 海老原敬、菊田英明:DNA microarray法による川崎病末梢白血球の遺伝子発現の解析。特定非営利活動法人日本川崎病研究センター、平成14年度事業報告。73-74


15. 菊田英明:小児呼吸器感染症とあらたに発見されたコロナウイルスHcoV-NL63. 感染・炎症・免疫 35巻、4号, 41-43,  2005

IV. A群β溶血性連鎖球菌関連

1. 菊田英明:最近、溶連菌感染症について思うこと。日本小児科医会会報 第35号、106-110, 2008


2. 菊田英明:マネジメントシリーズ、咽頭・扁桃炎のマネジメント、II. 咽頭・扁桃炎診療の手引き, 小児の診療、山中昇編、医薬ジャーナル社、190頁−199頁、2009


3. 菊田英明:A群β溶血性連鎖球菌感染症。化学療法の領域。26巻、8号、36-41, 2010.


4. 菊田英明:咽頭・扁桃炎。化学療法の領域。27巻、5号、34-94, 2011


5. 菊田 英明、柴田 睦郎、中田 修二、山中 樹、坂田 宏、小林 邦彦。臨床的に典型的なA群β溶血性レンサ球菌による咽頭・扁桃炎であるが迅速試験で陰性であった32例の咽頭培養細菌の検討。 小児感染免疫。第23巻、第3号、233-239, 2011


6. 菊田英明。小児科からみたA群β溶血性レンサ球菌による咽頭扁桃炎。日本耳鼻咽喉科学会会報。115巻、1-7、2012.


7. 菊田英明。保育園でよくある感染症−溶連菌、とびひ−保育と保険、2014年、20巻、4号、88-89ページ


V. 病原大腸菌

1. 菊田 英明、涌嶋三津子、西川 禎一。小児の散発性下痢症から分離され、O 群血清型分類が可能であった大腸菌の病原遺伝子保有率の評価。小児感染免疫。2013年、25巻、4号、413-419ページ。


2. 第5回北海道小児消化器病フォーラム 教育講演

散発性下痢症からO 群血清型分類された病原大腸菌検出の持つ意味  −病原遺伝子からみた評価− 菊田 英明、涌嶋三津子、西川 禎一

http://www.touei.or.jp/pdf/byougendaichoukin.pdf




研究業績(英文)


I. 著書

1.Kikuta, H, Mizuno, F, Yano, S and Osato, T: Epstein-Barr virus exposure and interferon production. pp190-191 (Rich, M A, Leukemia Reviews International Volume 1, Advanced in Comparative Leukemia Research, Marcel Dekker, Inc., New York and Basel) 1983


2. Osato, T, Kikuta, H, Okano, M, Mizuno, F, Konno, M, Ishikawa, N, Hirai, K and  Matsumoto, S: Kawasaki disease and Epstein-Barr virus infection. pp113-116 (Shulman, S T, Kawasaki disease, Alan R. Liss, Inc., New York) 1987


3. Osato, T, Mizuno, F, Aya, T, Koizumi, S, Imai, S, Matsuura, A, Kinoshita, T, Sugiura, M,  Kyi, H, Kikuta, H, Okano, M, Matsumoto, S, Abo, W, Yamanaka, T, Chiba, S, Nakao, T, Miyazaki, T, Miwa, M, Ohigashi, H, Koshimizu, K, Ito, Y, Harabuchi, Y, Kataura, A and Hirai, K: Infection and oncogenesis by ubiquitous human Epstein-Barr virus: unconrolled lymphoproliferation and risk factors. pp1-13 (Hokkaido University Medical Library Series, 124, Hokkaido University School of Medicine, Sappro) 1989


4. Kikuta, H: Human herpesvirus 6 (HHV-6) and exanthem subitum. pp137-144 (Ablashi, D V, Krueger, G V and Salahuddin, S Z, Human herpesvirus-6, Elsevier Science Publisher B.V. Amsterdam・London・New York・Tokyo) 1992

5. Ebihara T, Seya T, Kikuta H. Pathology of SARS. SARS. Mizutani T ed. Transworld Research Network. 61-75, 2006.


II. 綜説

1. Kikuta, H: Epstein-Barr virus-associated hemophagocytic syndrome. Leukemia Lymphoma 16, 425-429, 1995

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=7787752&query_hl=1&itool=pubmed_DocSum


2. Kikuta, H, Matsumoto, S and Osato T: Kawasaki disease and Epstein-Barr virus. Acta Paediatr Jpn 33, 765-770, 1991

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1666245&query_hl=1&itool=pubmed_DocSum


III. 原著

1. Konno, M, Kikuta, H, Ishikawa, N, Takada, K, Iwanaga, M and Osato, T: A possible association between hepatitis-B antigen-negative infantile papular acrodermatitis and Epstein-Barr virus infection. J Pediatr 101, 222-224, 1982

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6284902&query_hl=1&itool=pubmed_DocSum


2. Kikuta, H, Mizuno, F, Osato, T, Konno, M, Ishikawa, N, Noro, S-I and Sakurada, N: Kawasaki disease and an unusual primary infection with Epstein-Barr virus. Pediatrics 73, 413-414, 1984

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6322099&query_hl=1&itool=pubmed_DocSum


3. Kikuta, H, Mizuno, F, Yano, S and Osato, T: Interferon production by Epstein-Barr virus in human mononuclear leukocytes. J Gen Virol 65, 837-841, 1984

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=6323626&query_hl=1&itool=pubmed_DocSum


4. Koizumi, S, Fujiwara, S, Kikuta, H, Okano, M, Imai, S, Mizuno, F and Osato, T: Production of human monoclonal antibodies against Epstein-Barr virus-specific antigens by the virus-immortalized lymphoblastoid cell lines. Virology 150, 161-169, 1986

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=3006333&query_hl=1&itool=pubmed_DocSum


5. Kikuta, H, Sakiyama, Y, Matsumoto, S, Mizuno, F, Osato, T, Konno, M, Ishikawa, N, Uzuki, K, Haruo, N and Anakura, M: Possible causes of an unusual response to Epstein-Barr virus in patients with Kawasaki disease. Acta Paediatr Jpn 28, 120, 1986

6. Kikuta, H and Rapp F. Enhancement of Epstein-Barr virus gene expression by other herpesvirus. Intervirology 29, 281-291, 1988

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2848780&query_hl=1&itool=pubmed_DocSum


7. Kikuta, H, Taguchi, Y, Tomizawa, K, Kojima, K, Kawamura, N, Ishizaka, A, Sakiyama, Y, Matsumoto, S, Imai, S, Kinoshita, T, Koizumi, S, Osato, T, Kobayashi, I, Hamada, I and Hirai, K: Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection associated with Kawasaki-like disease. Nature 333, 455-457, 1988

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2836734&query_hl=1&itool=pubmed_DocSum


8. Kikuta, H, Lu, H, Matsumoto, S, Josephs, SF and Gallo, RC: Polymorphism of human herpesvirus 6 DNA from five Japanese patients with exanthema subitum. J Infect Dis 160, 550-551, 1989

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2547886&query_hl=1&itool=pubmed_DocSum


9. Kikuta, H, Nakanishi, M, Sakiyama, Y and Matsumoto, S: Chronic active Epstein-Barr virus (EBV) infection is associated with clonotypic intracellular terminal regions of the EBV. J Infect Dis 160, 546-547, 1989

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2547884&query_hl=1&itool=pubmed_DocSum


10. Kobayashi, I, Hamada, I, Tomizawa, K, Kikuta, H, Sakiyama Y and Matsumoto S: Chronic Epstein-Barr virus infections associated with coronary aneurysma. Acta Paediatr Jpn 31, 509-512, 1989

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2558492&query_hl=1&itool=pubmed_DocSum


11. Kikuta, H, Osato, T and Matsumoto, S: Sites of Epstein-Barr virus (EBV) replication in acute and chronic active EBV infections. Intervirology 30: 346-350, 1989

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2559902&query_hl=1&itool=pubmed_DocSum


12. Kikuta, H, Lu, H and Matsumoto S: Susceptibility of human herpesvirus 6 to acyclovir. Lancet ii, 861, 1989

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2571777&query_hl=1&itool=pubmed_DocSum


13. Kikuta, H, Lu, H, Tomizawa, K and Matsumoto, S: Enhancement of human herpesvirus 6 replication in adult human lymphocytes by monoclonal antibody to CD3. J Infect Dis 161, 1085-1087, 1990

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2161036&query_hl=1&itool=pubmed_DocSum


14. Kikuta, H, Nakane, A, Lu, H, Taguchi, Y, Minagawa, T and Matsumoto, S: Interferon induction by human herpesvirus 6 in human mononuclear cells. J Infect Dis 162, 35-38, 1990

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1693942&query_hl=1&itool=pubmed_DocSum


15. Kikuta, H, Matsumoto, S, Yanase, Y, Kawasaki, T, Mizuno, F and Osato, T: Recurrence of Kawasaki disease and Epstein-Barr virus infection. J Infect Dis 162, 121, 1990

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=2172398&query_hl=1&itool=pubmed_DocSum


16. Kikuta, H, Nakabayashi, T, Sagawa, T, Osato, T and Matsumoto, S: Isolation of Epstein-Barr virus (EBV) type B in Japan – A useful marker for EBV transformation –. Immunol Infect Dis 1, 29-31, 1990


17. Kikuta, H, Itami, N, Matsumoto, S, Chikaraishi, T and Togashi, M: Frequent detection of human herpesvirus 6 DNA in peripheral blood mononuclear cells from kidney transplant patients. J Infect Dis 163, 925, 1991

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1849169&query_hl=1&itool=pubmed_DocSum


18. Kikuta, H, Nakanishi, M, Ishikawa, N, Konno, M and Matsumoto, S: Detection of Epstein-Barr virus sequences in patients with Kawasaki disease by means of the polymerase chain reaction. Intervirology 33, 1-5, 1992

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1310957&query_hl=1&itool=pubmed_DocSum


19. Inoue, N, Kikuta, H and Yanagi, K: Comparative sequence analyses of Epstein-Barr virus-2 isolate. Intervirology 33, 180-186, 1992

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1339417&query_hl=1&itool=pubmed_DocSum


20. Okano, M, Kikuta, H, Abo, W, Koizumi, S, Aya, T, Yano, S, Takada, K, Mizuno, F and Osato, T: Frequent association of Epstein-Barr virus in Japanese patients with Burkitt’s lymphoma. Jpn J Clin Oncol 22, 320-324, 1992

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1281896&query_hl=1&itool=pubmed_DocSum


21. Kikuta, H, Sakiyama, Y, Matsumoto, S, Hamada, I, Yazaki, M, Iwaki, T and Nakano, M: Detection of Epstein-Barr virus (EBV) DNA in cardiac and aortic tissues from chronic active EBV infection associated with Kawasaki disease-like coronary aneurysms. J Pediatr 123, 90-92, 1993

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8391571&query_hl=1&itool=pubmed_DocSum


22. Muso, E, Fujiwara, H, Yoshida, H, Hosokawa, R, Yashiro, M, Hongo, Y, Matsumiya, T, Yamabe, H, Kikuta, H, Hironaka, T, Hirai, K and Kawai, C: Epstein-Barr virus genome-positive tubulo-interstitial nephritis with Kawasaki disease-like coronary aneurysma. Clin Nephrol 40, 7-15, 1993

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8395370&query_hl=1&itool=pubmed_DocSum


23. Nakanishi, M, Kikuta, H, Tomizawa, K, Kojima, K, Ishizaka, A, Okano, M, Sakiyama, Y and Matsumoto, S: Distinct clonotypic Epstein-Barr virus-induced fatal lymphoproliferative disorder in a patient with Wiskott-Aldrich syndrome. Cancer 72, 1376-1381, 1993

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8393374&query_hl=1&itool=pubmed_DocSum


24. Kikuta, H, Sakiyama, Y, Matsumoto, S, Oh-Ishi, T, Nakano, T, Nagashima, T, Oka, T, Hironaka, T and Hirai, K: Fatal Epstein-Barr virus-associated hemophagocytic syndrome. Blood 82, 3259-3264, 1993

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8241498&query_hl=1&itool=pubmed_DocSum


25. Kikuta, H and Sakiyama, Y: Etoposide (VP-16) inhibits Epstein-Barr virus determined nuclear antigen (EBNA) synthesis. Brit J Haematol 90, 971-972, 1995

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=7669686&query_hl=1&itool=pubmed_DocSum


26. Narita, M, Yamada, S, Matsuzono, Y, Itakura, O, Togashi, T and Kikuta, H: Immunoglobulin G avidity testing in serum and cerebrospinal fluid for analysis of Measles virus infection. Clin Diagn Lab Immunol 3, 211-215, 1996

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8991638&query_hl=1&itool=pubmed_DocSum


27. Koizumi, H, Ohgawara, A, Itakura, O and Kikuta H: Herpesviru-like DNA sequences in classic Kaposi’s sarcoma and angiosarcoma in Japan. Brit J Dermatol 135, 1009-1010, 1996

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8977735&query_hl=1&itool=pubmed_DocSum


28. Narita, M, Matsuzono, Y, Itakura, O, Togashi, T and Kikuta H: Survey of mycoplasmal bacteremia detected in children by polymerase chain reaction. Clin Infect Dis 23, 522-525, 1996

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8879774&query_hl=1&itool=pubmed_DocSum


29. Itakura, O, Yamada, S, Narita, M and, Kikuta, H: High prevalence of a 30-bp deletion and single-base mutations within the carboxy terminal end and the LMP-1 oncogene of Epstein-Barr virus in the Japanese population. Oncogene 13, 1549-1553, 1996

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8875994&query_hl=1&itool=pubmed_DocSum


30. Kikuta, H, Itakura, O, Ariga, T and Kobaashi, K: Detection of human herpesvirus 8 (HHV-8) DNA sequences in peripheral blood mononuclear cells of Japanese children. J Med Virol 53, 81-84, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9298737&query_hl=1&itool=pubmed_DocSum


31. Narita, M, Togashi, T and Kikuta, H: Neonatal measles in Hokkaido, Japan. Pediatr Infect J 25, 387-392, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9306490&query_hl=1&itool=pubmed_DocSum


32. Kikuta, H, Itakura, O, Taneichi, K and Kohno, M: Tropism of human herpesvirus 8 for peripheral blood lymphocytes in patients with Castleman’s disease. Brit J Haematol 99, 790-793, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9432023&query_hl=1&itool=pubmed_DocSum


33. Narita, M, Yamada, S, Matsuzono, Y, Itakura, O, Togashi, T and Kikuta, H: Measles virus-specific immunoglobulin G subclass response in serum and cerebrospinal fluid. Clin Diag Virol 8, 233-239, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9406654&query_hl=1&itool=pubmed_DocSum


34. Narita, M, Matsuzono, Y, Takekoshi, Y, Yamada, S, Itakura, O, Kubota, M, Kikuta, H and Togashi, T. Analysis of Mumps vaccine failure by means of avidity testing for Mumps virus-specific immunoglobulin G. Clin Diagn Lab Immunol. 5, 799-803, 1998

http://cvi.asm.org/cgi/content/full/5/6/799?view=long&pmid=9801337


35. Okamura, A, Yoshioka, M, Kubota, M, Kikuta, H, Ishiko, H and Kobayashi, K: Detection of a novel DNA virus (TTV) sequence in peripheral blood mononuclear cells. J Med Virol 58, 174-177, 1999

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10335866&query_hl=1&itool=pubmed_DocSum


36. Nagasaka, H, Kobayashi, K, Yorifuji, T, Kage, M, Kimura, A, Takayanagi, M, Kikuta, H, Egawa, H, Tanaka, K, Inui, A, Fujisawa, T and Ohtake, A: Indian childhood cirrhosis-like disease in a Japanese boy undergoing liver transplantation. J Pediatr Gastroentero Nutr 29, 598-600, 1999

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10554131&query_hl=1&itool=pubmed_DocSum


37. Komatsu, H, Inui, A, Koike, Y, Fujisawa, T, Suga, S, Ishizaki, T, Yamada, A and Kikuta H: Detection of human herpesvirus 7 DNA in cerebrospinal fluid of a child with exanthema subitum. Pediatr Int 42, 103-105, 2000

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10703249&query_hl=1&itool=pubmed_DocSum


38. Okamura, A, Yoshioka, M, Kikuta, H, Kubota, M, Ma, X, Hayashi, A, Ishiko, H and Kobayashi K: Detection of TT virus sequences in children with liver disease of unknown etiology. J Med Virol 62, 104-108, 2000

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10935996&query_hl=1&itool=pubmed_DocSum


39. Narita, M, Yamada, S, Kikuta, H, and Togashi, T: Reconstitution of humoral immunity during pregnancy. Am J Reprod Immunol 44, 148-152, 2000

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11028901&query_hl=1&itool=pubmed_DocSum


40. Ma, X, Okamura, A, Yoshioka, M, Ishiguro, N, Kikuta, H and Kobayashi K: No mutations of SAP/SH2D1A/DSHP and perforin genes in patients with Epstein-Barr virus-associated hemophagocytic syndrome in Japan. J Med Virol 65, 358-361, 2001

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11536244&query_hl=1&itool=pubmed_DocSum


41. Yoshioka, M, Ishiguro, N, Ishiko, H, Ma, X, Kikuta H and Kobayashi K: Heterogeneous, restricted patterns of Epstein-Barr virus latent gene expression in patients with chronic active Epstein-Barr virus infection. J Gen Virol 82, 2385-2392, 2001

http://vir.sgmjournals.org/cgi/content/full/82/10/2385


42. Ariga, T, Oda, N, Yamaguchi, K, Kawamura, N, Kikuta, H, Taniuchi, S, Kobayashi, S, Terada, K, Ikeda, H, Hershfield, MS, Kobayashi, K and Sakiyama, Y: T-cell lines from 2 patients with adenosine deaminase (ADA) deficiency showed the restoration of ADA activity resulted from the reversion of an inherited mutation. Blood 97, 2896-2899, 2001

http://www.bloodjournal.org/cgi/content/full/97/9/2896


43. Nagasaka, H, Chiba, H, Kikuta, H, Akita, H, Takahashi, Y, Yanai, H, Hui, S-P, Fuda, H, Fujiwara, H and Kobayashi K: Unique character and metabolism of high density lipoprotein (HDL) in fetus. Atherosclerosis 161, 215-223, 2002

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11882335&query_hl=1&itool=pubmed_DocSum

 

44. Ma, X, Kikuta, H, Ishiguro, N, Yoshioka, M, Ebihara, T, Murai, T, Kobayashi, I and Kobayashi, K: Association of prtF1 (encoding fibronectin-binding protein F1) and sic (encoding streptococcal inhibitor of complement) genes with emm types of group A streptococci isolated from Japanese children with pharyngitis. J Clin Microbiol 40, 3835-3837, 2002

http://jcm.asm.org/cgi/content/full/40/10/3835?view=long&pmid=12354893


45. Yoshioka, M, Kikuta, H, Ishiguro, N, Ma, X and Kobayashi, K: Unique Epstein–Barr virus (EBV) latent gene expression, EBNA promoter usage and EBNA promoter methylation status in chronic active EBV infection. J Gen Virol 84, 1133-1140, 2003

http://vir.sgmjournals.org/cgi/content/full/84/5/1133


46. Ebihara, T, Endo, R, Kikuta, H, Ishiguro, N, Yoshioka, M, Ma, X and Kobayashi K: Seroprevalence of human metapneumovirus in Japan. J Med Virol 70, 281-283, 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12696118&query_hl=1&itool=pubmed_DocSum


47. Yoshioka, M, Kikuta, H, Ishiguro, N, Endo, R and Kobayashi K. Latency pattern of Epstein-Barr virus and methylation status in Epstein-Barr virus-associated hemophagocytic syndrome. J Med Virol 70, 410-419, 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12767005&query_hl=1&itool=pubmed_DocSum


48. Nagasaka, H, Kikuta, H, Chiba, H, Murano, T, Harashima, H, Ohtake, A, Senzaki, H, Sasak,i N, Inou, I, Katayama, S, Shirai, K and Kobayashi K: Two cases with transient lipoprotein lipase (LPL) activity impairment: evidence for the involvement of an LPL inhibitor. Eur J Pediatr 162, 132-138, 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12655414&query_hl=1&itool=pubmed_DocSum


49. Terai, I, Kobayashi, K, Matsushita, M, Miyakawa, H, Mafune, N, Kikuta, H: Relationship between gene polymorphism of mannose-binding lectin (MBL) and two molecular forms of MBL. Eur J Immunol 33, 2755-2763, 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14515259&query_hl=1&itool=pubmed_DocSum


50. Nagasaka, H, Kikuta, H, Komatsu, H, Yorifuji, T, Egawa, H, Matsui A, Tanaka, K, Chiba, H and Kobayashi, K: Apolipoprotein E and apolipoprotein E-rich high-density cholesterol in cord blood as potential predict markers of congenital biliary tract anomalies. J Pediatr 143: 411, 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14558526&query_hl=1&itool=pubmed_DocSum


51. Ishiguro, N, Takada, A, Yoshioka, M, Ma, X, Kikuta, H, Kida, H and Kobayashi, K: Induction of Interferon-Inducible Protein-10 and monokine induced by interferon-γ from human endothelial cells infected with influenza A. virus. Arch Virol 149: 17-34, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14689273&query_hl=1&itool=pubmed_DocSum


52. Ebihara, T, Endo, R, Kikuta, H, Ishiguro, N,Ishiko, H and Kobayashi K: Comparison of seroprevalences of human metapneumovirus and human respiratory syncytial virus. J Med Virol 72: 304-306, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14695674&query_hl=1&itool=pubmed_DocSum


53. Ebihara, T, Endo, R, Kikuta, H, Ishiguro, N, Ishiko, H, Hara, M, Takahashi, Y and Kobayashi, K: Human metapneumovirus infection in Japanese children. J Clin Micro 42: 126-132, 2004.

http://jcm.asm.org/cgi/content/full/42/1/126?view=long&pmid=14715742


54. Endo, R, Kikuta, H, Ebihara, T, Ishiguro, N and Kobayashi, K:.Possible involvement in oncogenesis of a single base mutation in an internal ribosome entry site of Epstein-Barr nuclear antigen 1 mRNA. J Med Virol 72: 630-634, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=14981766&query_hl=1&itool=pubmed_DocSum


55. Muller T, Langner C, Fuchsbichler A, Heinz-Erian P, Ellenmunter H, Schlenck B, Janecke AR, Bavdekar AR, Pradhan AM, Pandit A, Muller-Hocker J, Melter M, Kobayashi K, Nagasaka H, Kikuta H, MullerW, Jaffe R, Knisely AS, Sternlieb I, Tanner MS, Aztloukal K, Denk H: Hepatocelluar intermediate filament cytoskeletal alterations and Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis. Hepatology 39: 963-969, 2004.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15057900&query_hl=1&itool=pubmed_DocSum


56. Ishiguro N, Ebihara T, Endo R, Ma X, Kikuta H, Ishiko H, Kobayashi K: High genetic diversity of the attachment (G) protein of human metapneumovirus. J Clin Micro 42: 3406-3414, 2004

http://jcm.asm.org/cgi/content/full/42/8/3406?view=long&pmid=15297475


57. Nagasaka H, Komatsu H, Ohura T, SogoT, Inui A, Yorifuji T, Murayama K, Takayanagi M, Kikuta H, Kobayashi K: Nitric oxide synthesis in ornithine transcarbamylase deficiency: Possible involvement of low No synthesis in clinical manifestations of urea cycle defect. J Pediatr 145:259-262, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15289781&query_hl=1&itool=pubmed_DocSum


58. Endo R, Yoshioka M, Ebihara T, Ishiguro N, Kikuta H, Kobayashi K: Clonal expansion of multiphenotypic Epstein-Barr virus-infected lymphocytes in chronic active Epstein-Barr virus infection. Medical Hypotheses 63: 582-587, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15325000&query_hl=1&itool=pubmed_DocSum


59. Nagasaka H, Yorifuji T, Kikuta H, Kawai M, Murayama K, Egawa H, Fujisawa T, Sasaki N, Hasegawa M, Sumazaki R, Chiba H, Yasuda T, Tanaka K, Kobayashi K: Resistance to parathyroid hormone in two patients with familial intrahepatic cholestasis: possible involvement of ATP8B1 gene in calcium regulation. J. Pediatr. Gastroenterol. Nutr. 39:404-409, 2004

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15448432&query_hl=1&itool=pubmed_DocSum


60. Ebihara T, Endo R, Ishiguro N,Nakayama T, Sawada H, Kikuta H: Early Reinfection with Human Metapneumovirus in an Infant. J Clin Mirobiol 42:5944-5946, 2004.

http://jcm.asm.org/cgi/content/full/42/12/5944?view=long&pmid=15583349


61. Ishiguro N, Ebihara T, Endo R, Ma X, Shirotsuki R, Ochiai S, Ishiko H, Kikuta H: Immunofluorescence assay for detection of human metapneumovirus-specific antibodies by means of baculovirus-expressed fusion protein. CDLI 12: 202-205,2004.

http://cvi.asm.org/cgi/content/full/12/1/202?view=long&pmid=15643008


62. Ebihara T, Endo R, Ma X, Ishiguro N,Kikuta H: Detection of human coronavirus NL63 in young children with bronchiolitis. J Med Virol 75: 463-465, 2005.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15648061&query_hl=1&itool=pubmed_DocSum


63. Ebihara T, Endo R, Ma X, Ishiguro N, Kikuta H. Detection of human metapneumovirus antigens in nasopharyngeal secretions by an immunofluorescent antibody test. J Clin Micro 43: 1138-1141, 2005.

http://jcm.asm.org/cgi/content/full/43/3/1138?view=long&pmid=15750074


64. Harada S, Obayashi M, Suzuki C, Kitamura R, Eda H, Kikuta H, Satoh H, Sugihara K, Yanagi K. A monoclonal antibody that recognizes Epstein-Barr virus nuclear antigen 2 (EBNA 2) amino acids 1-58 does not react with EBNA 2 in native form, consistent with the self-association of EBNA 2 through the amino-terminus. Arch Virol. 150: 1033-1043, 2005.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15662486&query_hl=1&itool=pubmed_DocSum


65. Ebihara T, Endo R, Kikuta H, Ishiguro N, Ma X, Shimazu M, Otoguro T, Kobayashi K: Differential leukocyte gene expression of S100 protein family in Kawasaki disease. Eur J Pediatr 164: 427-431, 2005.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15838637&query_hl=1&itool=pubmed_docsum


66. Ebihara T, Endo R, Ma X,Ishiguro N,Kikuta H. Lack of association between HCoV-NH and Kawasaki disease. J Infect Dis 192: 351-352, 2005.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15962233&query_hl=1&itool=pubmed_docsum


67. Ma X, Endo R, Ebihara T, Ishiguro N, Ishiko H, Kikuta H. Production and characterization of neutralizing monoclonal antibodies against human metapneumovirus F protein. Hybridoma 24: 201-205, 2005.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16120026&query_hl=1&itool=pubmed_docsum


68. Ma X, Endo R, Ishiguro N, Ebihara T, Ishiko H, Ariga T, Kikuta H. Detection of human bocavirus in Japanese children with lower respiratory tract infections. J Clin Micro 44: 1132-1134, 2006.

http://jcm.asm.org/cgi/content/full/44/3/1132?view=long&pmid=16517912


69. Ishiguro N, Ebihara T, Endo R, Ma X, Kawai E, Ishiko H, Kikuta H. Detection of antibodies against human metapneumovirus by Western blot analysis using recombinant nucleocapsid and matrix proteins. J Med Virol 78: 1091-1095, 2006

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16789025&query_hl=1&itool=pubmed_docsum


70. Endo R, Ebihara T, Ishiguro N, Kikuta H, Kobayashi K. A single base mutation in an internal ribosome entry site of Epstein-Barr virus nuclear antigen 1 mRNA and Epstein-Barr virus-associated lymphoproliferative diseases. Res Adv in Microbiol 6: 11-21, 2006.


71. Kikuta H, Shibata M, Nakata S, Yamanaka T, Sakata H, Fujita K, Kobayashi K. Efficacy of antibiotic prophylaxis for intra-familial transmission of group A β-hemolytic streptococci. Pediatr Infect Dis 26: 139-41, 2007.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17259876&query_hl=1&itool=pubmed_docsum


72. Kikuta H, Ebihara T, Endo R, Ishiguro N, Sakata C, Ochiai S, Ishiko H, Gamo R, Sato T. Development of a rapid chromatographic immunoassay for detection of human metapneumovirus (hMPV) using monoclonal antibodies against nucleoprotein of hMPV. Hybridoma 26: 17-21, 2007.

http://www.liebertonline.com/doi/abs/10.1089/hyb.2006.034


73. Endo R,Ishiguro N, Kikuta H, Teramoto S,ShirkoohiR, Ma X, Ebihara T, Ishiko H, Ariga T. Seroepidemiology of Human Bocavirus in Hokkaido Prefecture of Japan. J Clin Micro 45: 3218–3223, 2007.

http://jcm.asm.org/cgi/content/abstract/45/10/3218


74. Ebihara T, Masuda H, Akazawa T, Shingai M, Kikuta H, Ariga T, Matsumoto M, Seya T. Induction of NKG2D ligands on human dendritic cells by TLR ligand stimulation and RNA virus infection. Int Immunol 19:1145-1155, 2007.

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=NKG2D%20Ebihara


75. Kikuta H, Sakata C, Gamo R, Ishizaka A, Koga Y, Konno M, Ogasawara Y, Sawada H, Taguchi Y, Takahashi Y, Yasuda K, Ishiguro N, Hayashi A, Ishiko H, Kobayashi K.

Comparison of a lateral-flow immunochromatography assay with real-time RT-PCR for detection of human metapneumovirus.

J Clin Microbiol. 2008, 46: 928-932

http://www.ncbi.nlm.nih.gov/pubmed/18174301?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum


76. Rika Endo, Takashi Ebihara, Nobuhisa Ishiguro, Shinobu Teramoto, Tadashi Ariga, Chikako Sakata, Akio Hayashi, Hiroaki Ishiko, and Hideaki Kikuta

Detection of four genetic subgroup-specific antibodies to human metapneumovirus attachment (G) protein in human serum

J Gen Virol 2008 89: 1970-1977.

http://vir.sgmjournals.org/cgi/content/abstract/89/8/1970


77. Shirogane Y, Takeda M, Iwasaki M, Ishiguro N, Takeuchi H, Nakatsu Y, Tahara M, Kikuta H, Yanagi Y. Efficient Multiplication of Human Metapneumovirus in Vero Cells Expressing the Transmembrane Serine Protease TMPRSS2. J Virol. 2008; 82: 8942-8946

http://jvi.asm.org/cgi/content/abstract/82/17/8942


78. Kikuta H, Shibata M, Nakata S, Yamanaka T, Sakata H, Akizawa K, Kobayashi K: Comparative study of 5-day and 10-day cefditoren pivoxil treatments for recurrent group A β-hemolytic streptococcus pharyngitis in children. International Journal of Pediatrics, Volume 2009, Article ID 863608, 5 pages. Online publication date: 1-Feb-2009.

http://www.hindawi.com/getarticle.aspx?doi=10.1155/2009/863608


79. Shirkoohi R, Endo R, Ishiguro N, Teramoto S, Kikuta H, Ariga T: Antibodies against structural (VP1 and VP2) and nonstructural (NP-1 and NS1) proteins of human bocavirus in human sera. Clin Vaccine Immunol. 2010; 17: 190-193

http://www.ncbi.nlm.nih.gov/pubmed/19955324?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=6


80. Chan-It W, Thongprachum A, Okitsu S, Nishimura S, Kikuta H, Baba T, Yamamoto A, Sugita K, Hashira S, Tajima T, Mizuguchi M, Ushijima H. Detection and genetic characterization of norovirus infections in children with acute gastroenteritis in Japan, 2007-2009. Clin Lab 2011; 57: 213-220

http://www.ncbi.nlm.nih.gov/pubmed/21500729


81. Pham NT, Chan-It W, Khamrin P, Nishimura S, Kikuta H, Sugita K, Baba T, Yamamoto A, Shimizu H, Okitsu S, Mizuguchi M, Ushijima H. Detection of human parechovirus in stool samples collected from children with acute gastroenteritis in Japan during 2007-2008. J Med Virol 2011; 83: 331-336

http://www.ncbi.nlm.nih.gov/pubmed/21181931


82. Chan-it W, Thongprachum A, Dey SK, Phan TG, Khamrin P, Okitsu S, Nishimura S, Kobayashi M, Kikuta H, Baba T, Yamamoto A, Sugita K, Hashira S, Tajima T, Ishida S, Mizuguchi M, Ushijima H. Detection and genetic characterization of rotavirus infections in non-hospitalized children with acute gastroenteritis in Japan, 2007-2009. Infect Genet Evol. 2011; 11: 415-522

http://www.ncbi.nlm.nih.gov/pubmed/21145986


83. Teramoto S, Kaiho M, Takano Y, Endo R, Kikuta H, Sawa H, Ariga T, Ishiguro N. Detection of KI polyomavirus and WU polyomavirus DNA by real-time PCR in nasopharyngeal swabs and in normal lung and lung adenocarcinoma tissues. Microbiol Immunol. 2011; 55: 525-530

http://www.ncbi.nlm.nih.gov/pubmed/21545509


84. Teramoto S, Koseki N, Yoshioka M, Matsunami Y, Yanazume N, Nawate M, Shikano T, Takahashi Y, Kikuta H, Ishiguro N. Pediatr Infect Dis J. 2011; 30: 918. WU Polyomavirus Infection Confirmed by Genetic and Serologic Tests in an Infant With Bronchitis.

http://www.ncbi.nlm.nih.gov/pubmed/21915023


85. Kikuta H, Shibata M, Nakata S, Yamanaka T, Sakata H, Akizawa K, Kobayashi K Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan. International Journal of Pediatrics Volume 2011 (2011), Article ID 143872, 8 pages doi:10.1155/2011/143872

http://www.hindawi.com/journals/ijped/2011/143872/


86. Koseki N, Teramoto S, Kaiho M, Yoshioka M, Takahashi Y, Nakayama T, Sawada H, Konno M, Ushijima H, Kikuta H, Ariga T, and Ishiguro N. Detection of human bocavirus 2-4 from nasopharyngeal swab samples collected from patients with respiratory tract infections. J Clin Microbiol. 2012; 50: 2118-2121.

http://jcm.asm.org/content/50/6/2118.abstract


87. Thongprachum A, Chan-It W, Khamrin P, Okitsu S, Nishimura S, Kikuta H, Yamamoto A, Sugita K, Baba T, Mizuguchi M, Maneekarn N, Hayakawa S, Ushijima H. Reemergence of New Variant G3 Rotavirus in Japanese Pediatric Patients, 2009-2011. Infect Genet Evol. 2012; 13C: 168-174.

http://www.ncbi.nlm.nih.gov/pubmed/23123146


88. Khamrin P, Thongprachum A, Kikuta H, Yamamoto A, Nishimura S, Sugita K, Baba T, Kobayashi M, Okitsu S, Hayakawa S, Shimizu H, Maneekarn N, Ushijima H. Three clusters of Saffold viruses circulating in children with diarrhea in Japan. Infection, Genetics and Evolution 2013; 13: 339?343

http://www.ncbi.nlm.nih.gov/pubmed/23183311


89. Koseki N, Kaiho M, Kikuta H, Oba K , Togashi T, Ariga T, Ishiguro N. Comparison of the Clinical Effectiveness of Zanamivir and Laninamivir Octanoate for Children with Influenza A(H3N2) and B in the 2011-2012 Season. Influenza Other Respir Viruses. 2013 Aug 19. doi: 10.1111/irv.12147

http://www.ncbi.nlm.nih.gov/pubmed/23953886


90. Ishiguro N, Koseki N, Kaiho M, Kikuta H, Togashi T, Watanabe T, Ariga T, Hokkaido Pediatric Respiratory Infection Study Group Sensitivity and Specificity of a Loop-Mediated Isothermal Amplification Assay for the Detection of Mycoplasma Pneumonia from Nasopharyngeal Swab Samples Compared with those of Real-time PCR. Clin Lab 2015; 61: 603-606

http://www.ncbi.nlm.nih.gov/pubmed/26118195


91. Ishiguro1 N, Koseki N, Kaiho M, Kikuta H et. al. Regional Differences in Prevalence of Macrolide Resistance among Pediatric Mycoplasma pneumoniae Infections in Hokkaido, Japan. Jpn. J. Infect. Dis., 2016; 69, 186-190

https://www.jstage.jst.go.jp/article/yoken/69/3/69_JJID.2015.054/_pdf


92. Ishiguro N, Koseki N, Kaiho M, Ariga T, Kikuta H, Togashi T, et al. Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. PLoS ONE 2017; 12: e0173635.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348022/


93. Sayaka Takanashi, Aksara Thongprachum, Shoko Okitsu, Shuichi Nishimura, Masaaki Kobayashi, Hideaki Kikuta, Atsuko Yamamoto, Kumiko Sugita, Tsuneyoshi Baba, Satoshi Hayakawa, Masashi Mizuguchi, Hiroshi Ushijima Clin. Lab. 2017; 63: 961-970 Molecular Epidemiological Traits of Group A Rotaviruses in Japanese Children During Transitional Period of Rotavirus Vaccine Implementation, 2011 - 2014

http://clinical-laboratory.de/eaop/download/2471


 

IV. 症例報告

1. Kikuta, H, Okano, M, Sasaki, H, Motokawa, T, Chiba, S and Sakiyama Y: Acquired cytomegarovirus infection in an infant -Serum interferon activity after transfer factor injection- Acta Paediatr Jpn 23, 233-234, 1981


2. Ohnuma, K, Toyoda, Y, Nishihira, H, Iguchi, A, Honda, K, Nagao, T, Kigasawa, H, Tanaka, Y and Kikuta, H: Aggressive natural killer (NK) cell lymphoma: report of a pediatric case and review of the literature. Leukemia Lymphoma 25, 387-392, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9168449&query_hl=1&itool=pubmed_DocSum


3. Sugiyama, K, Ito, M, Ichimi, R, Higashikawa, M, Kawasaki, H, Komada, Y, Sakurai, M, Wakiguchi, H, Kikuta, H and Fukayama, M: A case of Epstein-Barr virus infection with exophthalmos and ocular muscle swelling. Acta Paediatr Jpn 39, 694-697, 1997

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9447760&query_hl=1&itool=pubmed_DocSum


4. Kato, N, Yasukawa, K, Onozuka, T and Kikuta, H: Nasal and nasal- type T/NK-cell lymphoma with cutaneous involvement. J Am Acad Dermatol 40, 850-856, 1999

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=10321634&query_hl=1&itool=pubmed_DocSum


5. Okamura, A, Itakura, O, Yoshioka, M, Kubota, M, Kikuta, H and Kobayashi K: Unusual presentation of measles giant cell pneumonia in a patient with acquired immunodeficiency syndrome. Clin Infect Dis 32, e57-58, 2001

http://www.journals.uchicago.edu/CID/journal/issues/v32n3/000288/000288.html


6. Nagasaka, H, Yorifuji, T, Egawa, T, Kikuta, H, Tanaka, K and Kobayashi, K: Successful living-donor liver transplantation from an asymptomatic carrier mother in ornithine transcarbamylase deficiency. J Pediatr. 138, 432-434, 2001

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11241058&query_hl=1&itool=pubmed_DocSum


7. Kato, N, Isu, K and Kikuta, H: Absence of human herpesvirus 8/Kaposi’s sarcoma-associated herpesvirus in a case of benign lymphangioendothelioma associated with periosteal haemangioma. Brit J Dermatol 146, 157-158, 2002

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=11841387&query_hl=1&itool=pubmed_DocSum


8. Yoshioka, M, Ishiguro, N, Ma, X, Kikuta, H, Kodaira, J, Itoh, T and Kobayashi, K: Protein-loosing cytomegalovirus gastritis in a patient with Stevens-Johnson syndrome. Digestion 65, 234-237, 2002

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12239465&query_hl=1&itool=pubmed_DocSum






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